Liu, J.-H.; Lv, X.-J.; Liu, Y.-K.*, Asymmetric Retro-Claisen Reaction Catalyzed by Chiral Aza-Bisoxazoline–Zn(II) Complex: Enantioselective Synthesis of α-Arylated Ketones. Org. Lett. 2023,25, 1706-1710. You, Z.-H.; Liu, Y.-K.*, Asymmetric Organocatalytic Access to Spiro-fused Heterocyclic Compounds: E1cB Elimination Mediates Formal [4 + 2] Annulation. Org. Lett. 2022,24, 6288-6291. Li, Y.-J.; Lv, X.-J.; Liu, Y.-K.*, Enantioselective Michael Addition/Cyclization/Desymmetrization Sequence of Prochiral Cyclic Hemiacetals and Nitroolefins: Synthesis of Chiral Oxygen-Bridged Bicyclic Compounds. Org. Lett. 2022,24, 9254-9258. Dong, H.; Wang, L.; Guo, M.; Stagos, D.; Giakountis, A.; Trachana, V.; Lin, X.; Liu, Y.-K.*; Liu, M., Antioxidant and Anticancer Activities of Synthesized Methylated and Acetylated Derivatives of Natural Bromophenols. In Antioxidants2022; Vol. 11. Wu, H.-C.; Wang, C.; Chen, Y.-H.; Liu, Y.-K.*, Asymmetric organocatalytic vinylogous Michael addition triggered triple-cascade reactions of 2-hydroxycinnamaldehydes and vinylogous nucleophiles: construction of benzofused oxabicyclo[3.3.1]nonane scaffolds. Chem. Commun. 2021,57, 1762-1765. Peng, C.-J.; Pei, J.-P.; Chen, Y.-H.; Wu, Z.-Y.; Liu, M.; Liu, Y.-K.*, Enantioselective organocatalytic sequential Michael-cyclization of functionalized nitroalkanes to 2-hydroxycinnamaldehydes: synthesis of benzofused dioxa[3.3.1] and oxa[4.3.1] methylene-bridged compounds. Org. Chem. Front. 2021,8, 4217-4223. Ming, Y.-C.; Lv, X.-J.; Liu, M.; Liu, Y.-K.*, Synthesis of Chiral Polycyclic Tetrahydrocarbazoles by Enantioselective Aminocatalytic Double Activation of 2-Hydroxycinnamaldehydes with Dienals. Org. Lett. 2021,23, 6515-6519. Lv, X.-J.; Ming, Y.-C.; Wu, H.-C.; Liu, Y.-K.*, Brønsted acid-catalyzed dynamic kinetic resolution of in situ formed acyclic N,O-hemiaminals: cascade synthesis of chiral cyclic N,O-aminals. Org. Chem. Front. 2021,8, 6309-6316. Du, G.-X.; Sun, C.-X.; Liu, Y.-K.*; Dong, Q.; Gao, P.; Li, D.-H.; Qu, L.-Y., In vitro anti-parasitic activity and mechanism of β-carboline derivatives isolated from the extracellular product of Salinivibrio proteolyticus strain YCSC6. Aquaculture 2021,534, 736337. Dong, S.; Chen, Z.; Wang, L.; Liu, Y.-K.*; Stagos, D.; Lin, X.; Liu, M., Marine Bromophenol Bis(2,3,6-Tribromo-4,5-Dihydroxybenzyl)ether Inhibits Angiogenesis in Human Umbilical Vein Endothelial Cells and Reduces Vasculogenic Mimicry in Human Lung Cancer A549 Cells. Mar Drugs 2021,19. Zhang, X. Q.; Lv, X. J.; Pei, J. P.; Tan, R.; Liu, Y.-K.*, An asymmetric multicatalytic reaction sequence of 2-hydroxycinnamaldehydes and enolic 1,3-dicarbonyl compounds to construct bridged bicyclic acetals. Org. Chem. Front. 2020,7, 292-297. Wu, G. W.; Yu, G. H.; Yu, Y. J.; Yang, S.; Duan, Z. W.; Wang, W.; Liu, Y.-K.*; Yu, R. L.; Li, J.; Zhu, T. J.; Gu, Q. Q.; Li, D. H., Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion. J. Med. Chem. 2020,63, 6924-6940. Pei, J.-P.; Lv, X.-J.; Peng, C.-J.; Liu, Y.-K.*, Asymmetric organocatalytic multicomponent reactions for efficient construction of bicyclic compounds bearing bisacetal and isoxazolidine moieties. Chem. Commun. 2020,56, 12765-12768. You, Z. H.; Chen, Y. H.; Tang, Y.; Liu, Y.-K.*, Application of E1cB Elimination in Asymmetric Organocatalytic Cascade Reactions To Construct Polyheterocyclic Compounds. Org. Lett. 2019,21, 8358-8363. Xie, C.-C.; Tan, R.; Liu, Y.-K.*, Asymmetric construction of polycyclic indole derivatives with different ring connectivities by an organocatalysis triggered two- step sequence. Org. Chem. Front. 2019,6, 919-924. Wang, C.; Chen, Y.-H.; Wu, H.-C.; Wang, C.; Liu, Y.-K.*, The Quinary Catalyst–Substrate Complex Induced Construction of Spiro-Bridged or Cagelike Polyheterocyclic Compounds via a Substrate-Controlled Cascade Process. Org. Lett. 2019,21, 6750-6755. Qiao, L.; Duan, Z. W.; Chen, Y. H.; Luang, Y. P.; Gu, Q. Q.; Liu, Y.-K.*; Li, D. H., Aspergiolides A and B: Core Structural Establishment and Synthesis of Structural Analogues. J. Org. Chem. 2019,84, 4451-4457. Lv, X.-J.; Chen, Y.-H.; Liu, Y.-K.*, Two Competitive but Switchable Organocatalytic Cascade Reaction Pathways: The Diversified Synthesis of Chiral Acetal-Containing Bridged Cyclic Compounds. Org. Lett. 2019,21, 190-195. Lv, X. J.; Zhao, W. W.; Chen, Y. H.; Wan, S. B.; Liu, Y.-K.*, Organocatalytic asymmetric synthesis of both cis- and trans-configured pyrano[2,3-b]chromenes via different dehydration pathways. Org. Chem. Front. 2019,6, 1972-1976. Chen, Y.-H.; Lv, X.-J.; You, Z.-H.; Liu, Y.-K.*, Asymmetric Organocatalyzed Reaction Sequence To Synthesize Chiral Bridged and Spiro-Bridged Benzofused Aminals via Divergent Pathways. Org. Lett. 2019,21, 5556-5561. Chen, Y.-H.; Lv, X.-J.; You, Z.-H.; Liu, Y.-K.*, Asymmetric organocatalyzed reaction sequence of 2-hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines to construct diverse chiral bridged polycyclic aminals. Org. Chem. Front. 2019,6, 3725-3730. You, Z.-H.; Chen, Y.-H.; Tang, Y.; Liu, Y.-K.*, Organocatalytic Asymmetric Synthesis of Spiro-Bridged and Spiro-Fused Heterocyclic Compounds Containing Chromane, Indole, and Oxindole Moieties. Org. Lett. 2018,20, 6682-6686. Wu, X.-N.; You, Z.-H.; Liu, Y.-K.*, Different hybridized oxygen atoms controlled chemoselective formation of oxocarbenium ions: synthesis of chiral heterocyclic compounds. Org. Biomol. Chem. 2018,16, 6507-6520. Qiao, L.; Duan, Z.-W.; Wu, X.-N.; Li, D.-H.; Gu, Q.-Q.; Liu, Y.-K.*, Organocatalytic Diversity-Oriented Asymmetric Synthesis of Structurally and Stereochemically Complex Heterocycles. Org. Lett. 2018,20, 1630-1633. Pei, J.-P.; Chen, Y.-H.; Liu, Y.-K.*, Asymmetric Organocatalytic Sequential Reaction of Structurally Complex Cyclic Hemiacetals and Functionalized Nitro-olefins To Synthesize Diverse Heterocycles. Org. Lett. 2018,20, 3609-3612. Chen, Y.-H.; Li, D.-H.; Liu, Y.-K.*, Diversified Synthesis of Chiral Chromane-Containing Polyheterocyclic Compounds via Asymmetric Organocatalytic Cascade Reactions. Acs Omega 2018,3, 16615-16625. Che, Q.; Qiao, L.; Han, X. N.; Liu, Y.-K.*; Wang, W.; Gu, Q. Q.; Zhu, T. J.; Li, D. H., Anthranosides A-C, Anthranilate Derivatives from a Sponge-Derived Streptomyces sp CMN-62. Org. Lett. 2018,20, 5466-5469. Zhao, W.-W.; Liu, Y.-K.*, Enantio- and diastereoselective synthesis of tetrahydrofuro[2,3-b]furan-2(3H)-one derivatives and related oxygen heterocycles via an asymmetric organocatalytic cascade process. Org. Chem. Front. 2017,4, 2358-2363. You, Z.-H.; Chen, Y.-H.; Wu, X.-N.; Liu, Y.-K.*, Lactols in Asymmetric Sequential Organo- and Gold-Catalysis: Synthesis of Densely Functionalized Epimeric Bicyclic O,O-Acetals. Adv. Synth. Catal. 2017,359, 4260-4266. Liu, C.; Liu, Y.-K.*, Asymmetric Organocatalytic One-Pot, Two-Step Sequential Process to Synthesize Chiral Acetal-Containing Polycyclic Derivatives from Cyclic Hemiacetals and Enones. J. Org. Chem. 2017,82, 10450-10460. Li, J.-Y.; Yu, K.-W.; Xie, C.-C.; Liu, Y.-K.*, Lactols in an asymmetric aldol-desymmetrization sequence: access to tetrahydro-4H-furo[2,3-b]pyran-2-one and tetrahydro-4H-furo[2,3-b]furan-2-one derivatives. Org. Biomol. Chem. 2017,15, 1407-1417. Chen, Y. H.; Sun, X. L.; Guan, H. S.; Liu, Y.-K.*, Diversity-Oriented One-Pot Synthesis to Construct Functionalized Chroman-2-one Derivatives and Other Heterocyclic Compounds. J. Org. Chem. 2017,82, 4774-4783. Zhou, H. B.; Li, L. Y.; Wu, C. M.; Kurtan, T.; Mandi, A.; Liu, Y.-K.*; Gu, Q. Q.; Zhu, T. J.; Guo, P.; Li, D. H., Penipyridones A-F, Pyridone Alkaloids from Penicillium funiculosum. J. Nat. Prod. 2016,79, 1783-1790. You, Z.-H.; Chen, Y.-H.; Liu, Y.-K.*, From racemic precursors to fully stereocontrolled products: one-pot synthesis of chiral α-amino lactones and lactams. Org. Biomol. Chem. 2016,14, 6316-6327. Sun, X.-L.; Chen, Y.-H.; Zhu, D.-Y.; Zhang, Y.; Liu, Y.-K.*, Substrate-Controlled, One-Pot Synthesis: Access to Chiral Chroman-2-one and Polycyclic Derivatives. Org. Lett. 2016,18, 864-867. Li, Z. L.; Liu, C.; Tan, R.; Tong, Z. P.; Liu, Y.-K.*, Organocatalytic, Asymmetric [2+2+2] Annulation to Construct Six-Membered Spirocyclic Oxindoles with Six Continuous Stereogenic Centers. Catalysts 2016,6. Li, J.-Y.; Li, Z.-L.; Zhao, W.-W.; Liu, Y.-K.*; Tong, Z.-P.; Tan, R., One-pot, highly efficient, asymmetric synthesis of ring-fused piperidine derivatives bearing N,O- or N,N-acetal moieties. Org. Biomol. Chem. 2016,14, 2444-2453. Cai, P.-W.; You, Z.-H.; Xie, L.-H.; Tan, R.; Tong, Z.-P.; Liu, Y.-K.*, The Attractive Application of Lactol Chemistry: From Racemic Lactol to Natural Product Skeleton. Synthesis 2016,48, 2581-2594. Liu, Y.-K.*; Li, Z.-L.; Li, J.-Y.; Feng, H.-X.; Tong, Z.-P., Open-Close: An Alternative Strategy to α-Functionalization of Lactone via Enamine Catalysis in One Pot under Mild Conditions. Org. Lett. 2015,17, 2022-2025. Feng, H.-X.; Tan, R.; Liu, Y.-K.*, An Efficient One-Pot Approach to the Construction of Chiral Nitrogen-Containing Heterocycles under Mild Conditions. Org. Lett. 2015,17, 3794-3797. Luan, Y. P.; Wei, H. J.; Zhang, Z. P.; Che, Q.; Liu, Y.-K.*; Zhu, T. J.; Mandi, A.; Kurtan, T.; Gu, Q. Q.; Li, D. H., Eleganketal A, a Highly Oxygenated Dibenzospiroketal from the Marine-Derived Fungus Spicaria elegans KLA03. J. Nat. Prod. 2014,77, 1718-1723. Chen, C.; Feng, H. X.; Li, Z. L.; Cai, P. W.; Liu, Y.-K.*; Shan, L. H.; Zhou, X. L., A highly efficient route to C-3 alkyl-substituted indoles via a metal-free transfer hydrogenation. Tetrahedron Lett. 2014,55, 3774-3776.
|